Product Data Sheet
MRS2279
Catalog No. A62869
MRS2279 is a selective antagonist of the P2Y1 receptor, demonstrated by a Ki value of 2.5 nM and an IC50 of 51.6 nM. This compound effectively inhibits ADP-induced platelet aggregation in a competitive manner, with an apparent affinity of pKB = 8.05. MRS2279 is valuable for research applications involving platelet function and signaling pathways related to purinergic receptors.
Chemical Information
| Catalog Num | A62869 |
|---|---|
| M. Wt | 469.71 |
| Formula | C13H18ClN5O8P2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 367909-40-8 |
| Synonyms | |
| SMILES | O=[P](O)(O)OC[C@]1([C@H]2O[P](O)(O)=O)[C@]([C@](N3C4=NC(Cl)=NC(NC)=C4N=C3)([H])C2)([H])C1 |
Biological Activity
| Description | MRS2279 is a selective antagonist of the P2Y1 receptor, demonstrated by a Ki value of 2.5 nM and an IC50 of 51.6 nM. This compound effectively inhibits ADP-induced platelet aggregation in a competitive manner, with an apparent affinity of pKB = 8.05. MRS2279 is valuable for research applications involving platelet function and signaling pathways related to purinergic receptors. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
