Clopidogrel-d3 hydrogen sulfate
Catalog No. A62877

Clopidogrel-d3 hydrogen sulfate is a deuterated form of Clopidogrel hydrogen sulfate, primarily designed as a stable isotope for pharmacokinetic studies. This compound functions as a potent antiplatelet agent, preventing blood clot formation by inhibiting platelet aggregation induced by ADP. Clopidogrel-d3 hydrogen sulfate also selectively inhibits cytochrome P450 isoforms CYP2B6 and CYP2C19, with IC50 values of 18.2 nM and 524 nM, respectively. Its usage is instrumental in research involving antithrombotic therapies and drug metabolism.
Chemical Information
| Catalog Num | A62877 |
|---|---|
| M. Wt | 422.92 |
| Formula | C16H15D3ClNO6S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1217643-68-9 |
| Synonyms | (S)-(+)-Clopidogrel bisulfate-d3; (S)-(+)-Clopidogrel-d3 hydrogen sulfate |
| SMILES | O=S(O)(O)=O.[2H]C([2H])([2H])OC([C@H](C1=C(C=CC=C1)Cl)N2CC3=C(SC=C3)CC2)=O |
Biological Activity
| Description | Clopidogrel-d3 hydrogen sulfate is a deuterated form of Clopidogrel hydrogen sulfate, primarily designed as a stable isotope for pharmacokinetic studies. This compound functions as a potent antiplatelet agent, preventing blood clot formation by inhibiting platelet aggregation induced by ADP. Clopidogrel-d3 hydrogen sulfate also selectively inhibits cytochrome P450 isoforms CYP2B6 and CYP2C19, with IC50 values of 18.2 nM and 524 nM, respectively. Its usage is instrumental in research involving antithrombotic therapies and drug metabolism. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


