Product Data Sheet
Adenosine 3'-phosphate 5'-phosphosulfate triethylamine
Catalog No. A62894
Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a selective antagonist of the P2Y1 receptor, exhibiting no activity against P2Y2, P2Y4, or P2Y6 receptors. This compound effectively inhibits ADP-induced platelet aggregation, as well as ADP-mediated shape changes and Ca2+ elevations in platelets, while not affecting ADP's inhibition of stimulated adenylate cyclase. Additionally, it serves as a co-substrate for the sulfonation of glycans and is valuable in Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays for transferring sulfonate groups.
Chemical Information
| Catalog Num | A62894 |
|---|---|
| M. Wt | |
| Formula | C16H30N6O13P2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 936827-87-1 |
| Synonyms | |
| SMILES | CCN(CC)CC.O[C@H]1[C@](O[C@@H]([C@H]1OP(O)(O)=O)COP(OS(=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[x] |
Biological Activity
| Description | Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a selective antagonist of the P2Y1 receptor, exhibiting no activity against P2Y2, P2Y4, or P2Y6 receptors. This compound effectively inhibits ADP-induced platelet aggregation, as well as ADP-mediated shape changes and Ca2+ elevations in platelets, while not affecting ADP's inhibition of stimulated adenylate cyclase. Additionally, it serves as a co-substrate for the sulfonation of glycans and is valuable in Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays for transferring sulfonate groups. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
