Product Data Sheet
Adenosine 3'-phosphate 5'-phosphosulfate lithium
Catalog No. A62898
Adenosine 3'-phosphate 5'-phosphosulfate lithium is a selective antagonist of the P2Y1 receptor, exhibiting no activity against P2Y2, P2Y4, or P2Y6 receptors. It effectively inhibits ADP-induced platelet aggregation, as well as ADP's ability to induce shape change and Ca2+ mobilization in platelets, without affecting ADP-stimulated adenylate cyclase activity. Furthermore, this compound acts as a co-substrate for glycan sulfonation and can be utilized in Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays to facilitate the transfer of sulfonate groups.
Chemical Information
| Catalog Num | A62898 |
|---|---|
| M. Wt | |
| Formula | C10H15N5O13P2S.xLi |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 109434-21-1 |
| Synonyms | |
| SMILES | O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OS(=O)(O)=O)(O)=O)([H])N2C3=NC=NC(NP(O)(O)=O)=C3N=C2.[Li].[x] |
Biological Activity
| Description | Adenosine 3'-phosphate 5'-phosphosulfate lithium is a selective antagonist of the P2Y1 receptor, exhibiting no activity against P2Y2, P2Y4, or P2Y6 receptors. It effectively inhibits ADP-induced platelet aggregation, as well as ADP's ability to induce shape change and Ca2+ mobilization in platelets, without affecting ADP-stimulated adenylate cyclase activity. Furthermore, this compound acts as a co-substrate for glycan sulfonation and can be utilized in Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays to facilitate the transfer of sulfonate groups. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
