Product Data Sheet
TCV-309 chloride
Catalog No. A62934
TCV-309 chloride is a highly effective antagonist of platelet-activating factor (PAF). It demonstrates specificity in inhibiting PAF-induced aggregation in both rabbit and human platelets, with IC50 values of 33 nM, 58 nM, and 27 nM for the corresponding assays. Additionally, TCV-309 chloride has exhibited potential therapeutic benefits in conditions such as anaphylactic shock, making it a valuable tool for research into PAF-related pathways and inflammatory responses.
Chemical Information
| Catalog Num | A62934 |
|---|---|
| M. Wt | 629.97 |
| Formula | C30H34BrClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 121494-09-5 |
| Synonyms | |
| SMILES | CCC[N+]1=CC(C(N(CCC(NCCOC(N2CC3=C(C=CC=C3)CC2)=O)=O)C4=CC=CC=C4)=O)=CC(Br)=C1.[Cl-] |
Biological Activity
| Description | TCV-309 chloride is a highly effective antagonist of platelet-activating factor (PAF). It demonstrates specificity in inhibiting PAF-induced aggregation in both rabbit and human platelets, with IC50 values of 33 nM, 58 nM, and 27 nM for the corresponding assays. Additionally, TCV-309 chloride has exhibited potential therapeutic benefits in conditions such as anaphylactic shock, making it a valuable tool for research into PAF-related pathways and inflammatory responses. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
