Product Data Sheet

Bepafant

Catalog No. A62973

main product photo
Bepafant is a specific antagonist of the platelet-activating factor receptor (PAFR) that demonstrates protective effects against anaphylactic lethality in both active and passive anaphylaxis models in mice and guinea pigs. This compound has been shown to reduce bronchoconstriction and mitigate blood pressure alterations associated with anaphylaxis. Bepafant is valuable for research focused on anaphylactic responses and the modulation of PAF-related pathways.
Chemical Information
Catalog NumA62973
M. Wt467.97
FormulaC23H22ClN5O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.114776-28-2
SynonymsWeb2170
SMILESO=C(C1CC2=C(C1)C(C(C3=C(Cl)C=CC=C3)=NCC4=NN=C(C)N45)=C5S2)N6CCOCC6
Biological Activity
DescriptionBepafant is a specific antagonist of the platelet-activating factor receptor (PAFR) that demonstrates protective effects against anaphylactic lethality in both active and passive anaphylaxis models in mice and guinea pigs. This compound has been shown to reduce bronchoconstriction and mitigate blood pressure alterations associated with anaphylaxis. Bepafant is valuable for research focused on anaphylactic responses and the modulation of PAF-related pathways.
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