Product Data Sheet

L662,025

Catalog No. A62987

main product photo
L662,025 is a potent and irreversible antagonist of the platelet-activating factor (PAF) receptor. It demonstrates a strong binding affinity with an IC50 value of 1 μM for receptor binding and effectively inhibits platelet aggregation at an IC50 value of 5.6 μM. This compound is primarily utilized in research applications focused on delineating the biological roles of PAF in various physiological and pathological processes.
Chemical Information
Catalog NumA62987
M. Wt441.48
FormulaC23H27N3O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.122328-38-5
Synonyms
SMILESCOC1=C(OC)C(OC)=CC([C@H]2CC[C@H](C3=CC(OC)=C(OCC=C)C(N=[N+]=[N-])=C3)O2)=C1
Biological Activity
DescriptionL662,025 is a potent and irreversible antagonist of the platelet-activating factor (PAF) receptor. It demonstrates a strong binding affinity with an IC50 value of 1 μM for receptor binding and effectively inhibits platelet aggregation at an IC50 value of 5.6 μM. This compound is primarily utilized in research applications focused on delineating the biological roles of PAF in various physiological and pathological processes.
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