Product Data Sheet
ONO-AE 248
Catalog No. A63030
ONO-AE 248 is a selective agonist of the EP3 prostaglandin receptor, exhibiting notable cardioprotective properties. It significantly reduces myocardial infarction size by specifically targeting the EP3α receptor in murine models, with its beneficial effects occurring independently of hemodynamic changes. The protective mechanism may involve the activation of protein kinase C and the opening of K(ATP) channels, highlighting its potential utility in cardiovascular research.
Chemical Information
| Catalog Num | A63030 |
|---|---|
| M. Wt | 380.52 |
| Formula | C22H36O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 211230-67-0 |
| Synonyms | |
| SMILES | CCCCC[C@H](OC)/C=C/[C@@H]1[C@H](C(C[C@H]1OC)=O)C/C=C\CCCC(O)=O |
Biological Activity
| Description | ONO-AE 248 is a selective agonist of the EP3 prostaglandin receptor, exhibiting notable cardioprotective properties. It significantly reduces myocardial infarction size by specifically targeting the EP3α receptor in murine models, with its beneficial effects occurring independently of hemodynamic changes. The protective mechanism may involve the activation of protein kinase C and the opening of K(ATP) channels, highlighting its potential utility in cardiovascular research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
