Product Data Sheet
SC 51089 free base
Catalog No. A63033
SC 51089 free base acts as a selective antagonist of the prostaglandin E2 EP1 receptor, displaying inhibitory constants (Kis) of 1.3 μM for EP1, 11.2 μM for TP, 17.5 μM for EP3, and 61.1 μM for FP receptors. This compound demonstrates notable neuroprotective activity, making it valuable for research in neurobiology and inflammation studies. Its specificity towards the EP1 receptor positions SC 51089 free base as an important tool for investigating the effects of prostaglandin signaling in various biological systems.
Chemical Information
| Catalog Num | A63033 |
|---|---|
| M. Wt | 422.86 |
| Formula | C22H19ClN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 146033-03-6 |
| Synonyms | |
| SMILES | O=C(N1C2=CC(Cl)=CC=C2OC3=CC=CC=C3C1)NNC(CCC4=CC=NC=C4)=O |
Biological Activity
| Description | SC 51089 free base acts as a selective antagonist of the prostaglandin E2 EP1 receptor, displaying inhibitory constants (Kis) of 1.3 μM for EP1, 11.2 μM for TP, 17.5 μM for EP3, and 61.1 μM for FP receptors. This compound demonstrates notable neuroprotective activity, making it valuable for research in neurobiology and inflammation studies. Its specificity towards the EP1 receptor positions SC 51089 free base as an important tool for investigating the effects of prostaglandin signaling in various biological systems. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
