Product Data Sheet
Tafluprost acid
Catalog No. A63037
Tafluprost acid is a selective agonist of the prostanoid FP receptor, demonstrating high affinity with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Its binding affinity for the prostanoid EP3 receptor is significantly lower, with an IC50 of 67 nM, indicating a preferential interaction with the FP receptor. Tafluprost acid is primarily utilized in glaucoma research, making it a valuable tool for studies focused on intraocular pressure regulation and ocular pharmacology.
Chemical Information
| Catalog Num | A63037 |
|---|---|
| M. Wt | 410.45 |
| Formula | C22H28F2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 209860-88-8 |
| Synonyms | AFP-172 |
| SMILES | O[C@H]([C@@H]1C/C=C\CCCC(O)=O)C[C@H]([C@@H]1/C=C/C(F)(COC2=CC=CC=C2)F)O |
Biological Activity
| Description | Tafluprost acid is a selective agonist of the prostanoid FP receptor, demonstrating high affinity with Ki and EC50 values of 0.4 nM and 0.53 nM, respectively. Its binding affinity for the prostanoid EP3 receptor is significantly lower, with an IC50 of 67 nM, indicating a preferential interaction with the FP receptor. Tafluprost acid is primarily utilized in glaucoma research, making it a valuable tool for studies focused on intraocular pressure regulation and ocular pharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
