Product Data Sheet
BAY 73-1449
Catalog No. A63047
BAY 73-1449 is a highly potent and selective antagonist of the prostacyclin receptor (IP), demonstrating an IC50 of less than 0.1 nM in cAMP assays using human HEL cells and rat dorsal root ganglion (DRG) neurons. This compound serves as a valuable tool in research aimed at elucidating the role of prostacyclin signaling in cardiovascular physiology, particularly in studies focused on blood pressure regulation.
Chemical Information
| Catalog Num | A63047 |
|---|---|
| M. Wt | 425.48 |
| Formula | C26H23N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 693790-96-4 |
| Synonyms | |
| SMILES | O=C(O)[C@@H](CC1=CC=CC=C1)NC2=NC=NC(C3=CC=C(OCC4=CC=CC=C4)C=C3)=C2 |
Biological Activity
| Description | BAY 73-1449 is a highly potent and selective antagonist of the prostacyclin receptor (IP), demonstrating an IC50 of less than 0.1 nM in cAMP assays using human HEL cells and rat dorsal root ganglion (DRG) neurons. This compound serves as a valuable tool in research aimed at elucidating the role of prostacyclin signaling in cardiovascular physiology, particularly in studies focused on blood pressure regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
