Product Data Sheet
RO3244794
Catalog No. A63064
RO3244794 is a potent and selective antagonist of the prostacyclin receptor (IP receptor), demonstrating a pKi value of 7.7 in human platelets and 6.9 in a recombinant IP receptor system. This compound shows significant analgesic and anti-inflammatory properties, making it a valuable tool for researchers investigating pain mechanisms and inflammatory conditions. Its specificity and efficacy contribute to its potential applications in pharmacological studies related to cardiovascular diseases and other related disorders.
Chemical Information
| Catalog Num | A63064 |
|---|---|
| M. Wt | 451.42 |
| Formula | C25H19F2NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 361457-01-4 |
| Synonyms | |
| SMILES | FC(C=C1)=CC=C1C[C@H](C(O)=O)NC(OCC2=CC3=CC(C4=CC=C(C=C4)F)=CC=C3O2)=O |
Biological Activity
| Description | RO3244794 is a potent and selective antagonist of the prostacyclin receptor (IP receptor), demonstrating a pKi value of 7.7 in human platelets and 6.9 in a recombinant IP receptor system. This compound shows significant analgesic and anti-inflammatory properties, making it a valuable tool for researchers investigating pain mechanisms and inflammatory conditions. Its specificity and efficacy contribute to its potential applications in pharmacological studies related to cardiovascular diseases and other related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
