Product Data Sheet
8-Isoprostaglandin E2
Catalog No. A63117
8-Isoprostaglandin E2 (iPE2-III) is a potent ligand for the thromboxane A2 receptor (TP). It is known to induce vasoconstriction and promote platelet aggregation, making it significant in vascular biology and hemostasis research. Additionally, 8-Isoprostaglandin E2 enhances the RANKL-dependent osteoclastic activity of marrow hematopoietic precursors through the cAMP signaling pathway, positioning it as a valuable agent in studies of bone metabolism and related disorders.
Chemical Information
| Catalog Num | A63117 |
|---|---|
| M. Wt | 352.47 |
| Formula | C20H32O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 27415-25-4 |
| Synonyms | iPE2-III |
| SMILES | CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C(C[C@H]1O)=O)C/C=C\CCCC(O)=O |
Biological Activity
| Description | 8-Isoprostaglandin E2 (iPE2-III) is a potent ligand for the thromboxane A2 receptor (TP). It is known to induce vasoconstriction and promote platelet aggregation, making it significant in vascular biology and hemostasis research. Additionally, 8-Isoprostaglandin E2 enhances the RANKL-dependent osteoclastic activity of marrow hematopoietic precursors through the cAMP signaling pathway, positioning it as a valuable agent in studies of bone metabolism and related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
