Product Data Sheet
17-Phenyl-18,19,20-trinor-PGD2
Catalog No. A63140
17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation that primarily targets adenosine diphosphate (ADP) signaling pathways. It demonstrates an IC50 of 8.4 μM, significantly outperforming prostaglandin D2 (PGD2), which has an IC50 of 18.6 nM. Additionally, 17-Phenyl-18,19,20-trinor-PGD2 serves as a weak agonist for cyclic AMP accumulation, making it a valuable tool for research in cardiovascular and hemostatic studies.
Chemical Information
| Catalog Num | A63140 |
|---|---|
| M. Wt | 386.48 |
| Formula | C23H30O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 85280-91-7 |
| Synonyms | 17-Phenyl-PGD2 |
| SMILES | OC(CCC/C=C\C[C@@H]1[C@H](C(C[C@@H]1O)=O)/C=C/[C@@H](O)CCC2=CC=CC=C2)=O |
Biological Activity
| Description | 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation that primarily targets adenosine diphosphate (ADP) signaling pathways. It demonstrates an IC50 of 8.4 μM, significantly outperforming prostaglandin D2 (PGD2), which has an IC50 of 18.6 nM. Additionally, 17-Phenyl-18,19,20-trinor-PGD2 serves as a weak agonist for cyclic AMP accumulation, making it a valuable tool for research in cardiovascular and hemostatic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
