Product Data Sheet

Nocloprost

Catalog No. A63171

main product photo
Nocloprost is an orally active agonist of the EP1 and EP3 receptors, functioning as a prostaglandin E2 (PGE2) analog. This compound demonstrates significant biological activity by inhibiting evoked [3H]ACh release, showcasing its potential in neuroprotective research. Nocloprost exhibits gastroprotective and ulcer-healing properties, effectively accelerating the healing of chronic gastric ulcers and promoting mucosal growth in experimental models. As such, it serves as a valuable reagent for studying gastrointestinal health and related therapeutics.
Chemical Information
Catalog NumA63171
M. Wt400.98
FormulaC22H37ClO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.79360-43-3
Synonyms
SMILESCCCCC(C)(C)[C@H](O)/C=C/[C@@H]1[C@H]([C@H](Cl)C[C@H]1O)C/C=C\CCCC(O)=O
Biological Activity
DescriptionNocloprost is an orally active agonist of the EP1 and EP3 receptors, functioning as a prostaglandin E2 (PGE2) analog. This compound demonstrates significant biological activity by inhibiting evoked [3H]ACh release, showcasing its potential in neuroprotective research. Nocloprost exhibits gastroprotective and ulcer-healing properties, effectively accelerating the healing of chronic gastric ulcers and promoting mucosal growth in experimental models. As such, it serves as a valuable reagent for studying gastrointestinal health and related therapeutics.
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