KT2-962
Catalog No. A63206

KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and a potent hydroxyl radical scavenger (IC50=500 nM). This compound has been shown to significantly reduce myocardial infarct size and the incidence of ventricular fibrillation. In a canine model of ischemia/reperfusion, KT2-962 demonstrated notable cardioprotective effects, making it valuable for research into myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases.
Chemical Information
| Catalog Num | A63206 |
|---|---|
| M. Wt | 518.02 |
| Formula | C23H25ClNNaO5S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 129648-96-0 |
| Synonyms | |
| SMILES | O=S(C1=C2C=CC(C(C)C)=CC=C2C(CCCCNS(=O)(C3=CC=C(C=C3)Cl)=O)=C1)(O[Na])=O |
Biological Activity
| Description | KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and a potent hydroxyl radical scavenger (IC50=500 nM). This compound has been shown to significantly reduce myocardial infarct size and the incidence of ventricular fibrillation. In a canine model of ischemia/reperfusion, KT2-962 demonstrated notable cardioprotective effects, making it valuable for research into myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


