Product Data Sheet
15-OH Tafluprost
Catalog No. A63217
15-OH Tafluprost is a synthetic analog of prostaglandin F2α (PGF2α) that targets prostaglandin receptors to modulate vascular responses. It effectively alleviates endothelin-1 (ET-1)-induced impairments in optic nerve head (ONH) blood flow and counteracts contraction of isolated ciliary artery segments. This compound is pertinent for investigating mechanisms of intraocular pressure regulation and potential therapeutic approaches for glaucoma-related vascular dysfunction.
Chemical Information
| Catalog Num | A63217 |
|---|---|
| M. Wt | 432.55 |
| Formula | C25H36O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 130209-78-8 |
| Synonyms | 16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor PGF2α isopropyl ester |
| SMILES | CC(C)OC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)COC2=CC=CC=C2)=O |
Biological Activity
| Description | 15-OH Tafluprost is a synthetic analog of prostaglandin F2α (PGF2α) that targets prostaglandin receptors to modulate vascular responses. It effectively alleviates endothelin-1 (ET-1)-induced impairments in optic nerve head (ONH) blood flow and counteracts contraction of isolated ciliary artery segments. This compound is pertinent for investigating mechanisms of intraocular pressure regulation and potential therapeutic approaches for glaucoma-related vascular dysfunction. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
