Product Data Sheet
9-deoxy-9-methylene Prostaglandin E2
Catalog No. A63247
9-deoxy-9-methylene Prostaglandin E2 is a stable isosteric analog of Prostaglandin E2 (PGE2) targeting prostaglandin receptors. It exhibits similar biological activity to PGE2 while demonstrating a reduced side effect profile. Research indicates that 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in lowering blood pressure in rats and effectively stimulates colonic activity in gerbils as well as uterine contractions in primates, making it valuable for studies on cardiovascular and reproductive physiology.
Chemical Information
| Catalog Num | A63247 |
|---|---|
| M. Wt | 350.49 |
| Formula | C21H34O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 61263-32-9 |
| Synonyms | 9-Deoxy-9-methylene PGE2 |
| SMILES | O[C@H]1[C@@H]([C@H](C(C1)=C)C/C=C\CCCC(O)=O)/C=C/[C@H](CCCCC)O |
Biological Activity
| Description | 9-deoxy-9-methylene Prostaglandin E2 is a stable isosteric analog of Prostaglandin E2 (PGE2) targeting prostaglandin receptors. It exhibits similar biological activity to PGE2 while demonstrating a reduced side effect profile. Research indicates that 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in lowering blood pressure in rats and effectively stimulates colonic activity in gerbils as well as uterine contractions in primates, making it valuable for studies on cardiovascular and reproductive physiology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
