Product Data Sheet
AL-12180
Catalog No. A63267
AL-12180 is a potent and selective FP-receptor agonist, exhibiting a Ki of 143 nM. This compound effectively stimulates the mobilization of intracellular Ca2+ in human trabecular meshwork (h-TM) and cardiac muscle (h-CM) cells, demonstrating EC50 values of 111 nM and 11 nM, respectively. AL-12180 is valuable for research applications investigating FP-receptor signaling pathways and related physiological processes.
Chemical Information
| Catalog Num | A63267 |
|---|---|
| M. Wt | 410.89 |
| Formula | C21H27ClO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 748816-43-5 |
| Synonyms | |
| SMILES | O=C(CC/C=C\CC[C@@H]1[C@H](OC[C@@H]1O)/C=C/[C@H](COC2=CC=CC(Cl)=C2)O)O |
Biological Activity
| Description | AL-12180 is a potent and selective FP-receptor agonist, exhibiting a Ki of 143 nM. This compound effectively stimulates the mobilization of intracellular Ca2+ in human trabecular meshwork (h-TM) and cardiac muscle (h-CM) cells, demonstrating EC50 values of 111 nM and 11 nM, respectively. AL-12180 is valuable for research applications investigating FP-receptor signaling pathways and related physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
