Product Data Sheet

19(S)-HETE

Catalog No. A63273

main product photo
19(S)-HETE is an arachidonic acid metabolite synthesized by cytochrome P450 enzymes and serves as a full orthosteric agonist of the prostacyclin (IP) receptor, exhibiting an EC50 value of 567 nM. Its biological activity includes inhibition of platelet activation and promotion of vascular relaxation. This compound is utilized in research exploring cardiovascular functions and the modulation of platelet activity.
Chemical Information
Catalog NumA63273
M. Wt320.47
FormulaC20H32O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.115461-40-0
Synonyms
SMILESC[C@H](O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
Biological Activity
Description19(S)-HETE is an arachidonic acid metabolite synthesized by cytochrome P450 enzymes and serves as a full orthosteric agonist of the prostacyclin (IP) receptor, exhibiting an EC50 value of 567 nM. Its biological activity includes inhibition of platelet activation and promotion of vascular relaxation. This compound is utilized in research exploring cardiovascular functions and the modulation of platelet activity.
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