Product Data Sheet
TASP0376377
Catalog No. A63295
TASP0376377 is a highly potent and selective antagonist of the CRTH2 receptor, exhibiting an IC50 of 13 nM. This compound demonstrates strong binding affinity for CRTH2, with an IC50 of 19 nM. TASP0376377 is valuable for research applications focusing on inflammatory responses and immune modulation, particularly in studies related to asthma, allergy, and other CRTH2-related pathways.
Chemical Information
| Catalog Num | A63295 |
|---|---|
| M. Wt | 479.31 |
| Formula | C25H16Cl2N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1233246-60-0 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(C=C1)C(C2=NC=C(C3=C2C=CC=C3)CC(O)=O)=O)C4=CC=C(C(Cl)=C4)Cl |
Biological Activity
| Description | TASP0376377 is a highly potent and selective antagonist of the CRTH2 receptor, exhibiting an IC50 of 13 nM. This compound demonstrates strong binding affinity for CRTH2, with an IC50 of 19 nM. TASP0376377 is valuable for research applications focusing on inflammatory responses and immune modulation, particularly in studies related to asthma, allergy, and other CRTH2-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
