Product Data Sheet

EP3 antagonist 6

Catalog No. A63305

main product photo
EP3 antagonist 6 is a selective EP3 receptor antagonist that demonstrates a potent inhibitory effect with an IC50 of 1.9 nM. This compound effectively blocks PGE2-induced uterine contractions in pregnant rat models, making it a valuable tool for exploring reproductive physiology and therapeutic interventions in uterine contractility. Its application in research can help elucidate the role of EP3 receptors in various biological processes.
Chemical Information
Catalog NumA63305
M. Wt487.63
FormulaC31H37NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.499149-94-9
Synonyms
SMILESCC(C)C[C@H](C1=CC(C)=CC(C)=C1)NC(C2=C(C=CC(COC3=C(C=CC=C3)C)=C2)CCC(O)=O)=O
Biological Activity
DescriptionEP3 antagonist 6 is a selective EP3 receptor antagonist that demonstrates a potent inhibitory effect with an IC50 of 1.9 nM. This compound effectively blocks PGE2-induced uterine contractions in pregnant rat models, making it a valuable tool for exploring reproductive physiology and therapeutic interventions in uterine contractility. Its application in research can help elucidate the role of EP3 receptors in various biological processes.
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