Product Data Sheet

AM432 sodium

Catalog No. A63311

main product photo
AM432 sodium is a selective antagonist of the CRTH2 receptor, also known as DP2. This compound exhibits high potency in human whole blood eosinophil assays, particularly under prolonged incubation conditions. Additionally, AM432 sodium has shown favorable pharmacokinetic profiles in canine and murine models of inflammatory diseases, making it a valuable tool for research in immunology and inflammatory pathways.
Chemical Information
Catalog NumA63311
M. Wt510.56
FormulaC29H31N2NaO5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1263409-34-2
Synonyms
SMILESO=C(O[Na])CC1=CC(C2=CC=C(C3=CC=C(OCC)N=C3)C=C2CN(C(C4CC4)=O)CC)=C(OC)C=C1
Biological Activity
DescriptionAM432 sodium is a selective antagonist of the CRTH2 receptor, also known as DP2. This compound exhibits high potency in human whole blood eosinophil assays, particularly under prolonged incubation conditions. Additionally, AM432 sodium has shown favorable pharmacokinetic profiles in canine and murine models of inflammatory diseases, making it a valuable tool for research in immunology and inflammatory pathways.
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