Product Data Sheet
CRTh2 antagonist 3
Catalog No. A63330
CRTh2 antagonist 3 is a potent antagonist of the chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2). This compound enhances the activity of phosphoinositide-dependent kinase-1 (PDK1) towards a short peptide substrate, exhibiting an EC50 of 2 μM and a Kd of 8.4 μM. Its potential applications include research into cardiovascular inflammation and the modulation of Th2-mediated responses.
Chemical Information
| Catalog Num | A63330 |
|---|---|
| M. Wt | 356.44 |
| Formula | C19H20N2O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 312928-72-6 |
| Synonyms | |
| SMILES | O=C(O)CN1C2=CC=CC=C2N=C1SCCOC3=C(C)C=CC=C3C |
Biological Activity
| Description | CRTh2 antagonist 3 is a potent antagonist of the chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2). This compound enhances the activity of phosphoinositide-dependent kinase-1 (PDK1) towards a short peptide substrate, exhibiting an EC50 of 2 μM and a Kd of 8.4 μM. Its potential applications include research into cardiovascular inflammation and the modulation of Th2-mediated responses. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
