Product Data Sheet
EP2 receptor agonist 2
Catalog No. A63332
EP2 receptor agonist 2 (compound 18a) is a highly selective G protein-biased agonist of the EP2 receptor, demonstrating an EC50 of 13 nM for hEP2G protein activation and minimal interaction with the β-arrestin pathway (EC50 > 10000 nM). This compound exhibits remarkable selectivity for the EP2 receptor, with EC50 values greater than 10000 nM for hEP1, hEP3, hEP4, hIP, and hFP. It serves as a valuable tool for research in inflammation and pain pathways, facilitating studies on EP2 receptor signaling and its therapeutic potential.
Chemical Information
| Catalog Num | A63332 |
|---|---|
| M. Wt | 375.44 |
| Formula | C19H21NO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1807780-00-2 |
| Synonyms | |
| SMILES | OC(C1=CSC([C@@H](CC2)O[C@](C[C@H]3O)([H])[C@@]2([H])[C@H]3COC4=CC=CC=C4)=N1)=O |
Biological Activity
| Description | EP2 receptor agonist 2 (compound 18a) is a highly selective G protein-biased agonist of the EP2 receptor, demonstrating an EC50 of 13 nM for hEP2G protein activation and minimal interaction with the β-arrestin pathway (EC50 > 10000 nM). This compound exhibits remarkable selectivity for the EP2 receptor, with EC50 values greater than 10000 nM for hEP1, hEP3, hEP4, hIP, and hFP. It serves as a valuable tool for research in inflammation and pain pathways, facilitating studies on EP2 receptor signaling and its therapeutic potential. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
