Product Data Sheet
L-657926
Catalog No. A63368
L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, exhibiting high selectivity and potency. The compound consists of two enantiomers: (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 0.27 nM, and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 124 nM. L-657926 is utilized in research focused on thromboxane signaling pathways, cardiovascular disease studies, and the modulation of related biological processes.
Chemical Information
| Catalog Num | A63368 |
|---|---|
| M. Wt | 371.83 |
| Formula | C21H19ClFNO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 113243-00-8 |
| Synonyms | |
| SMILES | FC1=CC=C(N(C2=C3CCC[C@H]2CC(O)=O)CC4=CC=C(C=C4)Cl)C3=C1 |
Biological Activity
| Description | L-657926 is a stereoselective antagonist of the thromboxane A2 (TxA2) receptor, exhibiting high selectivity and potency. The compound consists of two enantiomers: (-)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 0.27 nM, and (+)-9-chlorobenzyl-6-fluoro-1,2,3,4-tetrahydrocarbazol-1-yl acetic acid, with an IC50 of 124 nM. L-657926 is utilized in research focused on thromboxane signaling pathways, cardiovascular disease studies, and the modulation of related biological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
