Product Data Sheet
AGN 191976
Catalog No. A63377
AGN 191976 is a selective agonist of the thromboxane A2 (TP) receptor, exhibiting EC50 values of 0.23 nM in rat aorta and 24 nM in human platelets. This compound demonstrates significant intraocular pressure-lowering effects in canine and primate models. AGN 191976 serves as a valuable tool for investigating vascular biology and elucidating the role of thromboxane A2 in vascular function and related pathophysiological processes.
Chemical Information
| Catalog Num | A63377 |
|---|---|
| M. Wt | 380.48 |
| Formula | C21H32O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 159359-94-1 |
| Synonyms | |
| SMILES | O=C(CCC/C=C\C[C@H]1[C@]2(OC(O[C@@]([H])([C@@H]1/C=C/[C@H](CCCCC)O)C2)=O)[H])O |
Biological Activity
| Description | AGN 191976 is a selective agonist of the thromboxane A2 (TP) receptor, exhibiting EC50 values of 0.23 nM in rat aorta and 24 nM in human platelets. This compound demonstrates significant intraocular pressure-lowering effects in canine and primate models. AGN 191976 serves as a valuable tool for investigating vascular biology and elucidating the role of thromboxane A2 in vascular function and related pathophysiological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
