Product Data Sheet
17-trifluoromethylphenyl trinor Prostaglandin F2α
Catalog No. A63432
17-Trifluoromethylphenyl trinor Prostaglandin F2α is a potent agonist of the prostaglandin FP receptor, known for its significant biological activity as a luteolytic agent. This compound features a trifluoromethyl-substituted aromatic ring structure, akin to the phenoxy ring of travoprost, contributing to its efficacy in lowering intraocular pressure. Its pharmacological profile suggests potential applications in the treatment of glaucoma and other conditions where modulation of prostaglandin pathways is beneficial. Its luteolytic potency is comparable to or surpasses that of established agents such as fluprostenol and cloprostenol.
Chemical Information
| Catalog Num | A63432 |
|---|---|
| M. Wt | 456.50 |
| Formula | C24H31F3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 221246-34-0 |
| Synonyms | 17-Trifluoromethylphenyl trinor PGF2α |
| SMILES | O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](CCC2=CC(C(F)(F)F)=CC=C2)O)C/C=C\CCCC(O)=O |
Biological Activity
| Description | 17-Trifluoromethylphenyl trinor Prostaglandin F2α is a potent agonist of the prostaglandin FP receptor, known for its significant biological activity as a luteolytic agent. This compound features a trifluoromethyl-substituted aromatic ring structure, akin to the phenoxy ring of travoprost, contributing to its efficacy in lowering intraocular pressure. Its pharmacological profile suggests potential applications in the treatment of glaucoma and other conditions where modulation of prostaglandin pathways is beneficial. Its luteolytic potency is comparable to or surpasses that of established agents such as fluprostenol and cloprostenol. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
