Product Data Sheet
O-Desmethyl-N-deschlorobenzoyl Indomethacin
Catalog No. A63434
O-Desmethyl-N-deschlorobenzoyl Indomethacin is a metabolite of the non-steroidal anti-inflammatory drug indomethacin, acting as a cyclooxygenase (COX) inhibitor. This compound demonstrates significant biological activity by reducing the viability of HL-60 leukemia cells in the presence of glucose oxidase at a concentration of 600 μM. It serves as a valuable reagent in research focused on synthesizing prostaglandin D2 receptor antagonists and elucidating the metabolic pathways of NSAIDs.
Chemical Information
| Catalog Num | A63434 |
|---|---|
| M. Wt | 205.21 |
| Formula | C₁₁H₁₁NO₃ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 50995-53-4 |
| Synonyms | |
| SMILES | CC1=C(CC(=O)O)C2=C(C=CC(=C2)O)N1 |
Biological Activity
| Description | O-Desmethyl-N-deschlorobenzoyl Indomethacin is a metabolite of the non-steroidal anti-inflammatory drug indomethacin, acting as a cyclooxygenase (COX) inhibitor. This compound demonstrates significant biological activity by reducing the viability of HL-60 leukemia cells in the presence of glucose oxidase at a concentration of 600 μM. It serves as a valuable reagent in research focused on synthesizing prostaglandin D2 receptor antagonists and elucidating the metabolic pathways of NSAIDs. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
