Product Data Sheet

T26A

Catalog No. A63443

main product photo
T26A is a highly selective inhibitor of the prostaglandin transporter (PGT), specifically targeting PGT-mediated influx of prostaglandin E2 (PGE2). By blocking PGT activity, T26A effectively elevates extracellular PGE2 levels while reducing intracellular PGE2 metabolites and slowing the metabolism of injected PGE2 in Rattus norvegicus. This compound is valuable for research focused on understanding PGT function in adult animal models without affecting PGE2 synthesis.
Chemical Information
Catalog NumA63443
M. Wt729.79
FormulaC35H43N11O7
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.958860-12-3
Synonyms
SMILESO=C(NCCOCCOCCN=[N+]=[N-])C1=CC=C(NC2=NC(NCCOCCOCCNC(C3=CC=CC=C3)=O)=NC(NC4=CC=C(O)C=C4)=N2)C=C1
Biological Activity
DescriptionT26A is a highly selective inhibitor of the prostaglandin transporter (PGT), specifically targeting PGT-mediated influx of prostaglandin E2 (PGE2). By blocking PGT activity, T26A effectively elevates extracellular PGE2 levels while reducing intracellular PGE2 metabolites and slowing the metabolism of injected PGE2 in Rattus norvegicus. This compound is valuable for research focused on understanding PGT function in adult animal models without affecting PGE2 synthesis.
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