Product Data Sheet
AZ8838
Catalog No. A63461
AZ8838 is a potent, competitive allosteric antagonist of proteinase-activated receptor 2 (PAR2), exhibiting a pKi of 6.4 for human PAR2. This non-peptide small molecule displays significant inhibitory activity, making it valuable for research investigating PAR2-related pathophysiological processes. Its oral bioavailability enhances its utility in in vivo studies focused on pain, inflammation, and other PAR2-mediated conditions.
Chemical Information
| Catalog Num | A63461 |
|---|---|
| M. Wt | 234.27 |
| Formula | C13H15FN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2100285-41-2 |
| Synonyms | |
| SMILES | O[C@H](C1=NC=CN1)C2=C(C=C(C=C2)F)CCC |
Biological Activity
| Description | AZ8838 is a potent, competitive allosteric antagonist of proteinase-activated receptor 2 (PAR2), exhibiting a pKi of 6.4 for human PAR2. This non-peptide small molecule displays significant inhibitory activity, making it valuable for research investigating PAR2-related pathophysiological processes. Its oral bioavailability enhances its utility in in vivo studies focused on pain, inflammation, and other PAR2-mediated conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
