Product Data Sheet

TFLLR-NH2

Catalog No. A63468

main product photo
TFLLR-NH2 is a selective agonist of the protease-activated receptor 1 (PAR1), exhibiting an EC50 value of 1.9 μM. This compound activates PAR1, a key receptor involved in various physiological processes, including inflammation and thrombosis. TFLLR-NH2 is valuable for research applications focused on the role of PAR1 in cellular signaling pathways and its implications in cardiovascular and neurological conditions.
Chemical Information
Catalog NumA63468
M. Wt647.81
FormulaC31H53N9O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.197794-83-5
Synonyms
SMILESCC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Biological Activity
DescriptionTFLLR-NH2 is a selective agonist of the protease-activated receptor 1 (PAR1), exhibiting an EC50 value of 1.9 μM. This compound activates PAR1, a key receptor involved in various physiological processes, including inflammation and thrombosis. TFLLR-NH2 is valuable for research applications focused on the role of PAR1 in cellular signaling pathways and its implications in cardiovascular and neurological conditions.
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