Product Data Sheet
SFNGGP-NH2
Catalog No. A63494
SFNGGP-NH2 is a bioactive peptide that targets Protease-Activated Receptors (PARs), specifically PAR-3. This peptide plays a role in modulating thrombin signaling pathways and has been implicated in itch responses, particularly in cutaneous mast cells. Studies suggest that while PAR-3 does not induce itching independently, its co-expression with PAR-4 enhances thrombin activity, indicating its role as a cofactor in transmembrane signaling. This makes SFNGGP-NH2 valuable for research on itch mechanisms and thrombin-related physiological processes.
Chemical Information
| Catalog Num | A63494 |
|---|---|
| M. Wt | 576.60 |
| Formula | C25H36N8O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 261521-21-5 |
| Synonyms | |
| SMILES | C(CNC(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CO)N)=O)=O)CC(N)=O)=O)=O)(=O)N2[C@H](C(N)=O)CCC2 |
Biological Activity
| Description | SFNGGP-NH2 is a bioactive peptide that targets Protease-Activated Receptors (PARs), specifically PAR-3. This peptide plays a role in modulating thrombin signaling pathways and has been implicated in itch responses, particularly in cutaneous mast cells. Studies suggest that while PAR-3 does not induce itching independently, its co-expression with PAR-4 enhances thrombin activity, indicating its role as a cofactor in transmembrane signaling. This makes SFNGGP-NH2 valuable for research on itch mechanisms and thrombin-related physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
