Product Data Sheet
BAY-386
Catalog No. A63498
BAY-386 is a potent Protease Activated Receptor-1 (PAR-1) antagonist that effectively inhibits the expression of pro-inflammatory factors such as MCP-1 and CXCL1 in human umbilical vein endothelial cells (HUVEC). This compound is valuable for research into inflammatory processes and vascular biology, providing insights into PAR-1 signaling pathways and their role in inflammation-related conditions.
Chemical Information
| Catalog Num | A63498 |
|---|---|
| M. Wt | 514.52 |
| Formula | C22H25F3N4O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1256941-06-6 |
| Synonyms | |
| SMILES | O=C(N1C[C@@H](C2=NC(C3CC3)=NO2)C[C@@H](C4=CC=C(OC(F)(F)F)C=C4)C1)N5CCS(CC5)(=O)=O |
Biological Activity
| Description | BAY-386 is a potent Protease Activated Receptor-1 (PAR-1) antagonist that effectively inhibits the expression of pro-inflammatory factors such as MCP-1 and CXCL1 in human umbilical vein endothelial cells (HUVEC). This compound is valuable for research into inflammatory processes and vascular biology, providing insights into PAR-1 signaling pathways and their role in inflammation-related conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
