Product Data Sheet
P4pal10
Catalog No. A63500
P4pal10 is a potent antagonist of the protease-activated receptor 4 (PAR4). It effectively inhibits platelet aggregation and tissue factor (TF)-induced thrombin generation, exhibiting significant anticoagulant and antithrombotic properties. Additionally, P4pal10 reduces carrageenan-induced edema and granulocyte infiltration, and demonstrates protective effects in murine models of myocardial ischemia/reperfusion injury. This compound is valuable for research applications focused on thrombotic disorders and cardiovascular protection.
Chemical Information
| Catalog Num | A63500 |
|---|---|
| M. Wt | 1409.72 |
| Formula | C65H112N22O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1021346-05-3 |
| Synonyms | |
| SMILES | [C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CCCCCCCCCCCCCCC)=O)CO)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C(NCC(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CC(C)C)=O)C)=O)=O)=O |
Biological Activity
| Description | P4pal10 is a potent antagonist of the protease-activated receptor 4 (PAR4). It effectively inhibits platelet aggregation and tissue factor (TF)-induced thrombin generation, exhibiting significant anticoagulant and antithrombotic properties. Additionally, P4pal10 reduces carrageenan-induced edema and granulocyte infiltration, and demonstrates protective effects in murine models of myocardial ischemia/reperfusion injury. This compound is valuable for research applications focused on thrombotic disorders and cardiovascular protection. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
