Product Data Sheet

RAS GTPase inhibitor 1

Catalog No. A63571

main product photo
RAS GTPase inhibitor 1 is a specific inhibitor targeting RAS GTPase, known for its significant anti-tumor activity. This compound demonstrates an effective EC50 of less than 1 μM in facilitating nucleotide exchange and an IC50 of less than 1 μM in H727 cancer cells. It is valuable for research applications aimed at understanding RAS signaling pathways and developing targeted cancer therapies.
Chemical Information
Catalog NumA63571
M. Wt565.99
FormulaC27H28ClF4N5O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2252242-32-1
Synonyms
SMILESCC[C@@H](NC1=C2C=CC=C(C3=CCNCC3)C2=NC(NC4=CC=C(F)C(Cl)=C4)=N1)C5CC5.O=C(O)C(F)(F)F
Biological Activity
DescriptionRAS GTPase inhibitor 1 is a specific inhibitor targeting RAS GTPase, known for its significant anti-tumor activity. This compound demonstrates an effective EC50 of less than 1 μM in facilitating nucleotide exchange and an IC50 of less than 1 μM in H727 cancer cells. It is valuable for research applications aimed at understanding RAS signaling pathways and developing targeted cancer therapies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.