Product Data Sheet
KRASG12D-IN-3
Catalog No. A63582
KRASG12D-IN-3 is a potent inhibitor that specifically targets the KRASG12D mutation. It demonstrates significant anti-proliferative effects on AGS and AsPC-1 cell lines, with IC50 values of 0.38 nM and 1.23 nM, respectively. This compound is valuable for research applications focused on the role of KRAS mutations in cancer biology and therapeutic development.
Chemical Information
| Catalog Num | A63582 |
|---|---|
| M. Wt | 682.06 |
| Formula | C31H30ClF6N7O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3033638-63-7 |
| Synonyms | |
| SMILES | ClC1=C(C(F)(F)F)C(C2=C(F)C(N=C(OC[C@]3(C/C(C4)=C(F)\F)N4CCC3)N=C5N(C[C@@H]6N[C@H]7CC6)[C@@H]7[C@H](C)O8)=C5C8=N2)=CC(N)=C1 |
Biological Activity
| Description | KRASG12D-IN-3 is a potent inhibitor that specifically targets the KRASG12D mutation. It demonstrates significant anti-proliferative effects on AGS and AsPC-1 cell lines, with IC50 values of 0.38 nM and 1.23 nM, respectively. This compound is valuable for research applications focused on the role of KRAS mutations in cancer biology and therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
