Product Data Sheet

KRAS inhibitor-20

Catalog No. A63608

main product photo
KRAS Inhibitor-20 is a small molecule inhibitor targeting the oncogenic mutant KRasG12C. It demonstrates potent inhibitory activity with an IC50 value of less than 10 nM, making it an effective tool for studying KRas-driven malignancies. This compound is valuable for research applications focused on cancer biology, offering insights into therapeutic strategies for KRas-related tumors.
Chemical Information
Catalog NumA63608
M. Wt604.68
FormulaC31H40F4N6O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2411786-32-6
Synonyms
SMILESC[C@H]1CN(C(C=C)=O)CCN1C2=NC(OC[C@H]3N(CCC3)C)=NC4=C2C[C@@H](C)[C@H](C5=C(F)C(N)=CC(C)=C5C(F)(F)F)C4
Biological Activity
DescriptionKRAS Inhibitor-20 is a small molecule inhibitor targeting the oncogenic mutant KRasG12C. It demonstrates potent inhibitory activity with an IC50 value of less than 10 nM, making it an effective tool for studying KRas-driven malignancies. This compound is valuable for research applications focused on cancer biology, offering insights into therapeutic strategies for KRas-related tumors.
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SHIPPING AND STORAGE
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