Product Data Sheet
SOS1-IN-7
Catalog No. A63633
SOS1-IN-7 is a selective inhibitor targeting SOS1, demonstrating potent activity with IC50 values of 20 nM for the SOS1-G12D mutant and 67 nM for the SOS1-G12V variant. This compound effectively disrupts SOS1-mediated signaling pathways, making it a valuable tool for investigating the roles of SOS1 in cancer biology. Its application in research may facilitate the development of therapeutic strategies against tumors driven by mutant RAS signaling.
Chemical Information
| Catalog Num | A63633 |
|---|---|
| M. Wt | 462.46 |
| Formula | C23H25F3N4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2755415-30-4 |
| Synonyms | |
| SMILES | C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC2=C3C(NC(C)=N2)=NC(C([C@@]4(CC[C@H](CC4)O)O)=C3)=O |
Biological Activity
| Description | SOS1-IN-7 is a selective inhibitor targeting SOS1, demonstrating potent activity with IC50 values of 20 nM for the SOS1-G12D mutant and 67 nM for the SOS1-G12V variant. This compound effectively disrupts SOS1-mediated signaling pathways, making it a valuable tool for investigating the roles of SOS1 in cancer biology. Its application in research may facilitate the development of therapeutic strategies against tumors driven by mutant RAS signaling. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
