Product Data Sheet
SOS1-IN-10
Catalog No. A63670
SOS1-IN-10 is a selective inhibitor of SOS1, exhibiting a potent inhibitory effect with an IC50 value of 13 nM specifically targeting the KRAS G12C-SOS1 interaction. This compound is valuable for research studying the role of SOS1 in oncogenic signaling pathways, particularly in cancer models driven by KRAS mutations. Its use can facilitate investigations into therapeutic strategies aimed at modulating RAS-dependent pathways.
Chemical Information
| Catalog Num | A63670 |
|---|---|
| M. Wt | 450.40 |
| Formula | C22H19F5N4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2758690-15-0 |
| Synonyms | |
| SMILES | C=C[C@H](C1=CC=CC(C(F)F)=C1F)NC2=NC(C)=NC3=CC(N(C=C32)C4(CC4)C(F)F)=O |
Biological Activity
| Description | SOS1-IN-10 is a selective inhibitor of SOS1, exhibiting a potent inhibitory effect with an IC50 value of 13 nM specifically targeting the KRAS G12C-SOS1 interaction. This compound is valuable for research studying the role of SOS1 in oncogenic signaling pathways, particularly in cancer models driven by KRAS mutations. Its use can facilitate investigations into therapeutic strategies aimed at modulating RAS-dependent pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
