Product Data Sheet

KRAS G12C Ligand-Linker Conjugates 1

Catalog No. A63694

main product photo
KRAS G12C Ligand-Linker Conjugates 1 is a conjugate formed from the KRAS G12C ligand and a linker moiety. This compound is designed to facilitate the targeted degradation of KRAS G12C proteins through the synthesis of PROTAC YF135. It serves as a valuable tool for studying KRAS-related signaling pathways and exploring therapeutic strategies in KRAS-driven cancers.
Chemical Information
Catalog NumA63694
M. Wt823.42
FormulaC45H55ClN8O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3033236-98-2
Synonyms
SMILESO=C(CCOCCCN1CCC[C@H]1COC2=NC3=C(C(N4CCN([C@H](C4)CC#N)C(/C(C#N)=C/C5CC5)=O)=N2)CCN(C3)C6=CC=CC7=C6C(Cl)=CC=C7)OC(C)(C)C
Biological Activity
DescriptionKRAS G12C Ligand-Linker Conjugates 1 is a conjugate formed from the KRAS G12C ligand and a linker moiety. This compound is designed to facilitate the targeted degradation of KRAS G12C proteins through the synthesis of PROTAC YF135. It serves as a valuable tool for studying KRAS-related signaling pathways and exploring therapeutic strategies in KRAS-driven cancers.
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