Product Data Sheet
Farnesyl thiosalicylic acid amide
Catalog No. A63697
Farnesyl thiosalicylic acid amide (FTS-A) is an orally active derivative that targets the farnesyl thiosalicylic acid pathway. It effectively reduces Ras-GTP levels, demonstrating significant inhibition of cell growth in Panc-1 and U87 cell lines, with IC50 values of 20 μM and 10 μM, respectively. This compound is relevant for cancer research, offering potential insights into Ras signaling and therapeutic strategies.
Chemical Information
| Catalog Num | A63697 |
|---|---|
| M. Wt | 357.55 |
| Formula | C22H31NOS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1092521-74-8 |
| Synonyms | FTS amide; Salirasib amide |
| SMILES | C/C(C)=C/CC/C(C)=C/CC/C(C)=C/CSC1=C(C=CC=C1)C(N)=O |
Biological Activity
| Description | Farnesyl thiosalicylic acid amide (FTS-A) is an orally active derivative that targets the farnesyl thiosalicylic acid pathway. It effectively reduces Ras-GTP levels, demonstrating significant inhibition of cell growth in Panc-1 and U87 cell lines, with IC50 values of 20 μM and 10 μM, respectively. This compound is relevant for cancer research, offering potential insights into Ras signaling and therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
