Product Data Sheet
SOS1-IN-13
Catalog No. A63773
SOS1-IN-13 is a potent inhibitor of son of sevenless homolog 1 (SOS1), exhibiting IC50 values of 6.5 nM for SOS1 and 327 nM for phosphorylated extracellular signal-regulated kinase (pERK). This compound is valuable in anticancer research, providing insights into the role of SOS1 in tumorigenesis and signaling pathways associated with cell proliferation and survival. Its high selectivity allows for targeted studies of SOS1-mediated mechanisms in various cancer models.
Chemical Information
| Catalog Num | A63773 |
|---|---|
| M. Wt | 405.41 |
| Formula | C21H22F3N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2654741-45-2 |
| Synonyms | |
| SMILES | COC1=C(C=C2C(C(C)=NN=C2N[C@@H](C3=CC=CC(C(F)(F)F)=C3C)C)=C1)OC |
Biological Activity
| Description | SOS1-IN-13 is a potent inhibitor of son of sevenless homolog 1 (SOS1), exhibiting IC50 values of 6.5 nM for SOS1 and 327 nM for phosphorylated extracellular signal-regulated kinase (pERK). This compound is valuable in anticancer research, providing insights into the role of SOS1 in tumorigenesis and signaling pathways associated with cell proliferation and survival. Its high selectivity allows for targeted studies of SOS1-mediated mechanisms in various cancer models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
