Product Data Sheet
CH 275
Catalog No. A63849
CH 275 is a peptide analog of somatostatin that selectively targets somatostatin receptor 1 (sst1) with a Ki of 52 nM. As a potent sst1 agonist, it exhibits an IC50 of 30.9 nM while demonstrating much lower affinities for human sst3, sst4, sst2, and sst5, with IC50 values of 345 nM, >1 μM, >10 μM, and >10 μM, respectively. CH 275 is valuable for researching the role of somatostatin in Alzheimer's disease and other neurodegenerative disorders.
Chemical Information
| Catalog Num | A63849 |
|---|---|
| M. Wt | 1485.77 |
| Formula | C74H96N14O15S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 174688-78-9 |
| Synonyms | |
| SMILES | C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N[C@@H](CC4=CC=C(CNC(C)C)C=C4)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CO)C(=O)N[C@H](C(O)=O)CSSC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@@H](CC7=CC=CC=C7)C(=O)N3)[H])[H] |
Biological Activity
| Description | CH 275 is a peptide analog of somatostatin that selectively targets somatostatin receptor 1 (sst1) with a Ki of 52 nM. As a potent sst1 agonist, it exhibits an IC50 of 30.9 nM while demonstrating much lower affinities for human sst3, sst4, sst2, and sst5, with IC50 values of 345 nM, >1 μM, >10 μM, and >10 μM, respectively. CH 275 is valuable for researching the role of somatostatin in Alzheimer's disease and other neurodegenerative disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
