Product Data Sheet
NF-56-EJ40
Catalog No. A63926
NF-56-EJ40 is a highly selective antagonist of the human SUCNR1 (GPR91), demonstrating potent inhibitory activity with an IC50 of 25 nM and a Ki of 33 nM. Its specificity minimizes interaction with rat SUCNR1, showcasing a Ki value of 17.4 nM when assessed against a humanized rat model. This compound is valuable for research applications targeting metabolic disorders and the role of SUCNR1 in physiological processes.
Chemical Information
| Catalog Num | A63926 |
|---|---|
| M. Wt | 443.54 |
| Formula | C27H29N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2380230-73-7 |
| Synonyms | |
| SMILES | O=C(NC1=C(CC(O)=O)C=CC=C1)C2=CC=CC(C3=CC=C(CN4CCN(C)CC4)C=C3)=C2 |
Biological Activity
| Description | NF-56-EJ40 is a highly selective antagonist of the human SUCNR1 (GPR91), demonstrating potent inhibitory activity with an IC50 of 25 nM and a Ki of 33 nM. Its specificity minimizes interaction with rat SUCNR1, showcasing a Ki value of 17.4 nM when assessed against a humanized rat model. This compound is valuable for research applications targeting metabolic disorders and the role of SUCNR1 in physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
