Product Data Sheet
NF-56-EJ40 hydrochloride
Catalog No. A63932
NF-56-EJ40 hydrochloride is a selective antagonist of the human SUCNR1 (GPR91) receptor, exhibiting an IC50 of 25 nM and a Ki of 33 nM. This compound demonstrates minimal activity against rat SUCNR1 while maintaining high affinity for humanized rat SUCNR1, evidenced by a Ki value of 17.4 nM. NF-56-EJ40 hydrochloride is suitable for research applications investigating the role of SUCNR1 in metabolic and cardiovascular diseases.
Chemical Information
| Catalog Num | A63932 |
|---|---|
| M. Wt | 516.46 |
| Formula | C27H31Cl2N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2728500-80-7 |
| Synonyms | |
| SMILES | O=C(NC1=C(CC(O)=O)C=CC=C1)C2=CC=CC(C3=CC=C(CN4CCN(C)CC4)C=C3)=C2.Cl.Cl |
Biological Activity
| Description | NF-56-EJ40 hydrochloride is a selective antagonist of the human SUCNR1 (GPR91) receptor, exhibiting an IC50 of 25 nM and a Ki of 33 nM. This compound demonstrates minimal activity against rat SUCNR1 while maintaining high affinity for humanized rat SUCNR1, evidenced by a Ki value of 17.4 nM. NF-56-EJ40 hydrochloride is suitable for research applications investigating the role of SUCNR1 in metabolic and cardiovascular diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
