Product Data Sheet
6-Methoxyflavanone
Catalog No. A63942
6-Methoxyflavanone is a flavonoid compound that acts as a positive allosteric modulator of GABAA receptors, specifically enhancing the activity of human recombinant α1β2γ2L and α2β2γ2L subtypes. This compound is capable of crossing the blood-brain barrier and demonstrates key biological activities including anti-anxiety effects, analgesic properties, and relief from neuropathic pain. Additionally, 6-Methoxyflavanone exhibits inhibitory activity towards bitter receptor hTAS2R39 and hTAS2R14, providing a reversible antagonistic effect. Its unique profile makes it a valuable tool for research in neuroscience and pharmacology.
Chemical Information
| Catalog Num | A63942 |
|---|---|
| M. Wt | 254.28 |
| Formula | C16H14O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3034-04-6 |
| Synonyms | 6-MeOF |
| SMILES | O=C1CC(C2=CC=CC=C2)OC3=CC=C(OC)C=C13 |
Biological Activity
| Description | 6-Methoxyflavanone is a flavonoid compound that acts as a positive allosteric modulator of GABAA receptors, specifically enhancing the activity of human recombinant α1β2γ2L and α2β2γ2L subtypes. This compound is capable of crossing the blood-brain barrier and demonstrates key biological activities including anti-anxiety effects, analgesic properties, and relief from neuropathic pain. Additionally, 6-Methoxyflavanone exhibits inhibitory activity towards bitter receptor hTAS2R39 and hTAS2R14, providing a reversible antagonistic effect. Its unique profile makes it a valuable tool for research in neuroscience and pharmacology. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
