Product Data Sheet

MS438

Catalog No. A63964

main product photo
MS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. By specifically binding to the serpentine region of TSHR, MS438 effectively induces T4 secretion in mice. This compound is valuable for research into thyroid function and disorders related to TSHR signaling.
Chemical Information
Catalog NumA63964
M. Wt390.36
FormulaC20H17F3N2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.512840-45-8
Synonyms
SMILESO=C(OCC1=CC=CC=C1)C2=C(NC(NC2C3=CC=C(C=C3)C(F)(F)F)=O)C
Biological Activity
DescriptionMS438 is a potent thyrotropin receptor (TSHR) agonist with an EC50 of 53 nM. By specifically binding to the serpentine region of TSHR, MS438 effectively induces T4 secretion in mice. This compound is valuable for research into thyroid function and disorders related to TSHR signaling.
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