Product Data Sheet
Mozavaptan-d6
Catalog No. A64038
Mozavaptan-d6 is a deuterium-labeled variant of Mozavaptan, a selective competitive antagonist of the vasopressin V2 receptor, with an IC50 of 14 nM. This compound exhibits approximately 85-fold selectivity for the V2 receptor compared to the V1 receptor, which has an IC50 of 1.2 μM. Mozavaptan-d6 is utilized in research studying the modulation of fluid balance and potential therapies for hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH), and congestive heart failure. Its stable isotope labeling enables advanced pharmacokinetic studies and metabolic profiling.
Chemical Information
| Catalog Num | A64038 |
|---|---|
| M. Wt | 433.58 |
| Formula | C27H23D6N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2750534-83-7 |
| Synonyms | OPC-31260-d6 |
| SMILES | O=C(C1=CC=C(C=C1)NC(C2=C(C=CC=C2)C)=O)N3C4=CC=CC=C4C(CCC3)N(C([2H])([2H])[2H])C([2H])([2H])[2H] |
Biological Activity
| Description | Mozavaptan-d6 is a deuterium-labeled variant of Mozavaptan, a selective competitive antagonist of the vasopressin V2 receptor, with an IC50 of 14 nM. This compound exhibits approximately 85-fold selectivity for the V2 receptor compared to the V1 receptor, which has an IC50 of 1.2 μM. Mozavaptan-d6 is utilized in research studying the modulation of fluid balance and potential therapies for hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH), and congestive heart failure. Its stable isotope labeling enables advanced pharmacokinetic studies and metabolic profiling. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
