12(S)-HPETE
Catalog No. A64068

12(S)-HPETE, a metabolite of 12-lipoxygenase, plays a crucial role in regulating vascular tone. It induces the expression of c-Fos and c-Jun proteins while increasing activating protein 1 (AP-1) activity in vascular smooth muscle cells. This compound may be pivotal in vasomotor regulation, influencing interactions between endothelial cells and adjacent blood cells. 12(S)-HPETE is useful for investigating cerebrovascular tension in various research contexts.
Chemical Information
| Catalog Num | A64068 |
|---|---|
| M. Wt | 336.47 |
| Formula | C20H32O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 71774-10-2 |
| Synonyms | |
| SMILES | CCCCC/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(O)=O |
Biological Activity
| Description | 12(S)-HPETE, a metabolite of 12-lipoxygenase, plays a crucial role in regulating vascular tone. It induces the expression of c-Fos and c-Jun proteins while increasing activating protein 1 (AP-1) activity in vascular smooth muscle cells. This compound may be pivotal in vasomotor regulation, influencing interactions between endothelial cells and adjacent blood cells. 12(S)-HPETE is useful for investigating cerebrovascular tension in various research contexts. |
|---|
RETURN POLICY
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


